Dynamic Coordination in the Brain - From Neurons to Mind

Dynamic Coordination in the Brain

Dynamic Coordination in the Brain: From Neurons to Mind (Strüngmann Forum Reports) [Hardcover] Christoph von der Malsburg (Editor), William A. Phillips (Editor), Wolf Singer (Editor). A fundamental shift is occurring in neuroscience and related disciplines. In the past, researchers focused on functional specialization of the brain, discovering complex processing strategies based on convergence and divergence in slowly adapting anatomical architectures. Yet for the brain to cope with ever-changing and unpredictable circumstances, it needs strategies with richer interactive short-term dynamics. Recent research has revealed ways in which the brain effectively coordinates widely distributed and specialized activities to meet the needs of the moment. This book explores these findings, examining the functions, mechanisms, and manifestations of distributed dynamical coordination in the brain and mind across different species and levels of organization.  It considers the role of dynamic coordination in temporally structured activity and explores these issues at different levels, from synaptic and local circuit mechanisms to macroscopic system dynamics, emphasizing their importance for cognition, behavior, and psychopathology.

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Annual Reports in Medicinal Chemistry, Volume 44 by John E. Macor

Annual Report in Medical
Chemistry Volume 44

Annual Reports in Medicinal Chemistry, Volume 44 by John E. Macor. Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. * Covers findings related to cardiovascular, inflammation, and pulmonary diseases * Examines issues in oncology, from mTor inhibitors to drug targets * Incorporates up-to-date information on drug design and discovery, including delivery to market. This volume provides reviews of six topics demonstrating the breadth of the field and recent successes in medicinal chemistry. Each of the first five chapters takes an important biochemical target as its theme and provides an insight into current progress in drug design.  The last chapter focuses on the vital subject of phamacokinetics and the great strides that have been made in this discipline during the past decade. Provides reviews of important topics in medicinal chemistry together with an emphasis on topics in the biological sciences, which are expected to provide the basis for future therapies. This book covers findings related to cardiovascular, inflammation, and pulmonary diseases. It examines issues in oncology, from mTor inhibitors to drug targets.

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